Tae-Kang Kim Selected Research

20-hydroxyvitamin D3

6/2021	Knocking out the Vitamin D Receptor Enhances Malignancy and Decreases Responsiveness to Vitamin D3 Hydroxyderivatives in Human Melanoma Cells.
1/2021	20S-Hydroxyvitamin D3, a Secosteroid Produced in Humans, Is Anti-Inflammatory and Inhibits Murine Autoimmune Arthritis.
5/2020	Noncalcemic Vitamin D Hydroxyderivatives Inhibit Human Oral Squamous Cell Carcinoma and Down-regulate Hedgehog and WNT/β-Catenin Pathways.
1/2020	CYP11A1-derived vitamin D3 products protect against UVB-induced inflammation and promote keratinocytes differentiation.
1/2018	On the role of classical and novel forms of vitamin D in melanoma progression and management.
2/2017	Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo models.
5/2015	Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1.
7/2014	RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.
12/2010	Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity.

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Tae-Kang Kim Research Topics

Disease

20	Melanoma (Melanoma, Malignant) 01/2022 - 03/2010
6	Neoplasms (Cancer) 01/2022 - 01/2013
4	Skin Neoplasms (Skin Cancer) 10/2023 - 10/2014
3	Fibrosis (Cirrhosis) 12/2021 - 01/2021
2	Skin Diseases (Skin Disease) 10/2023 - 01/2022
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 01/2013
2	Hypercalcemia (Milk Alkali Syndrome) 05/2020 - 12/2010
1	Ischemia 10/2023
1	Sarcoidosis (Schaumann Disease) 01/2022
1	Allergic Contact Dermatitis 01/2022
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2022
1	Carcinoma (Carcinomatosis) 01/2022
1	Neurodermatitis (Lichen Simplex Chronicus) 01/2022
1	Systemic Scleroderma (Systemic Sclerosis) 12/2021
1	Arthritis (Polyarthritis) 01/2021
1	Rheumatoid Arthritis 01/2021
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 11/2020
1	Squamous Cell Carcinoma of Head and Neck 05/2020
1	Glioma (Gliomas) 05/2020
1	Inflammation (Inflammations) 01/2020
1	COVID-19 01/2020
1	Actinic Keratosis 01/2020
1	Disease Progression 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2017
1	Smith-Lemli-Opitz Syndrome 07/2015
1	Carcinogenesis 09/2014
1	Leukemia 03/2010
1	Neointima 01/2010

Drug/Important Bio-Agent (IBA)

12	hydroxide ionIBA 12/2021 - 01/2011
10	Vitamin D FDA LinkGeneric 01/2022 - 09/2012
10	Calcitriol (Calcijex)FDA LinkGeneric 01/2022 - 12/2010
9	20-hydroxyvitamin D3IBA 06/2021 - 12/2010
7	Cholecalciferol (Vitamin D3)FDA Link 01/2022 - 12/2010
6	MelatoninIBA 10/2023 - 07/2013
5	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)IBA 10/2023 - 12/2010
5	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2022 - 09/2012
5	SecosteroidsIBA 10/2014 - 01/2011
4	AgarIBA 12/2017 - 09/2012
3	Vitamin D3 24-HydroxylaseIBA 01/2022 - 05/2015
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2018
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022 - 01/2018
3	CollagenIBA 12/2021 - 01/2021
3	1alpha,20-dihydroxyvitamin D3IBA 06/2021 - 01/2020
2	VitaminsIBA 01/2022 - 01/2020
2	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2022 - 01/2022
2	N-acetyl-N-formyl-5-methoxykynurenamineIBA 03/2015 - 07/2013
1	GTP-Binding Proteins (G-Protein)IBA 10/2023
1	AntigensIBA 01/2022
1	Hydroxyl RadicalIBA 01/2022
1	Matrix Metalloproteinases (MMPs)IBA 12/2021
1	Messenger RNA (mRNA)IBA 12/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 08/2021
1	Phosphates (Orthophosphate)IBA 06/2021
1	CalciumIBA 06/2021
1	CytokinesIBA 01/2021
1	AntibodiesIBA 01/2021
1	Collagen Type II (Type II Collagen)IBA 01/2021
1	CateninsIBA 05/2020
1	nasIBA 03/2020
1	Dihydrotachysterol (AT 10)IBA 03/2020
1	Serotonin (5 Hydroxytryptamine)IBA 03/2020
1	EnzymesIBA 01/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 01/2018
1	SteroidsIBA 07/2015
1	Melanins (Melanin)IBA 05/2015
1	Tyrosine (L-Tyrosine)FDA Link 03/2015
1	Protective AgentsIBA 09/2014
1	Interleukin-17 (Interleukin 17)IBA 07/2014
1	enhanced green fluorescent proteinIBA 09/2012
1	LigandsIBA 09/2012
1	1,25-dihydroxyvitamin DIBA 09/2012
1	DNA (Deoxyribonucleic Acid)IBA 03/2011
1	3,21-dihydroxypregna-5,7-dien-20-oneIBA 01/2011
1	3- hydroxyandrosta- 5,7- diene- 17- carboxylic acidIBA 03/2010
1	Cyclin D1IBA 01/2010
1	Phenobarbital (Luminal)FDA Link 01/2010
1	CyclinsIBA 01/2010

Therapy/Procedure

4	Therapeutics 10/2023 - 01/2013
1	Injections 08/2021
1	Chemoprevention 01/2020